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NAXEN®

 

Product Information (Abridged)

     
     
 

 
 
Properties
 

NAXEN® (naproxen) is a non-steroidal analgesic / anti-inflammatory drug (NSAID) belonging to the propionic acid group. NAXEN® is associated with rapid onset of pain relief and sustained anti-inflammatory effect. Apart from the proven clinical efficacy in rheumatic and non-rheumatic indications, NAXEN® enjoys a well established safety and tolerability profile, with over 25 years of worldwide clinical experience.

 
Indications  
   
Rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, acute gout, acute musculoskeletal disorders and dysmenorrhoea.
   
Dosage
 

Adults: Rheumatoid arthritis, osteoarthritis and ankylosing spondylitis, usually 500mg to 1g daily taken in two doses at 12 hours intervals or a single administration. Acute gout: 750 mg initially, then 250mg every eight hours until attack has passed. Acute musculoskeletal disorders and dysmenorrhoea: 500mg initially, then 250mg at 6 – 8 hours intervals with maximum daily dose after the first day of 1250mg.

 
Elderly: Use lowest effective dose.
 
Children: For juvenile arthritis in children over 5 years: 5mg/kg body weight twice daily.
 
Contraindication
 

Active peptic ulceration, Hypersensitivity to naproxen formulations. Aspirin / anti-inflammatory-induced allergy.

 
Side effects
 

GI – nausea, vomiting, pain, rarely bleeding, ulceration, stomatitis, colitis. Hepatorenal – rarely jaundice, fatal hepatitis, nephropathy, heamaturia. Dermatological/hypersensitivity – rashes, urticaria, alopecia, angio-oedema, photosensitivity, rarely vasculitis, erythema multiforme, stevens johnson syndrome. CNS – headache, insomnia, tinnitus, vertigo, visual / hearing disturbances, functional disorders, rarely aseptic meningitis.

 
Packs
 
Tablets (low excipient) 250mg  - 20, 200
Tablets (low excipient) 500mg  - 20, 100